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Article

Genome-wide screening of DNA methylation in bovine blastocysts with different kinetics of development

8 Jan 2018

Abstract excerpt

BACKGROUND: The timing of the first cell divisions may predict the developmental potential of an embryo, including its ability to establish pregnancy. Besides differences related to metabolism, stress, and survival, embryos with different speeds of development present distinct patterns of gene expression, mainly related to energy and lipid metabolism. As gene expression is regulated by epigenetic factors, and...

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PMID: 29310712
DOI: 10.1186/s13072-017-0171-z

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