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Article

DNA methylation profile of single in vitro matured bovine oocytes.

Molecular reproduction and development - 1 Apr 2023

Vargas Luna N, Caixeta Felippe M C, Dode Margot A N, Caetano Alexandre R, Franco Maurício M

Abstract excerpt

Somatic cell nuclear transfer (SCNT) is commercially used despite incomplete nuclear reprogramming of the somatic cell nucleus by the enucleated oocyte compromising its efficiency. Oocyte selection is a key factor in increasing this efficiency as its cytoplasm reprograms the differentiated cell. In this study, we adapted a methodology to characterize epialleles in potential epigenetic markers in single in vitro...

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PMID: 36852602
DOI: 10.1002/mrd.23679

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