Article
Global DNA Methylation Profiles of Buffalo (Bubalus Bubalis) Preimplantation Embryos Produced by Handmade Cloning and in Vitro Fertilization
2021-06-01
Abstract excerpt
Somatic cell nuclear transfer technique (SCNT) has proved to be an outstanding method of multiplication of elite animals but accompanied with low efficiency and live birth rate of cloned animals. Epigenetic alterations of DNA has been one of the culprits behind this issue. Cloned embryos are found to deviate slightly from regular pattern of demethylation and re-methylation at the time of nuclear reprogramming and...
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Identifiers and source
- Literature Corpus work
- 6f7234ff-bcaa-5aef-895d-d5b57c8a2827
- DOI
- 10.21203/rs.3.rs-550977/v1
