Article
ABCB1 C3435T polymorphism is associated with susceptibility to major depression, but not with a clinical response to citalopram in a Turkish population.
Pharmacological reports : PR - 1 Apr 2014
Ozbey Gul, Yucel Berna, Taycan Serap E, Kan Derya, Bodur Nurdan E, Arslan Tayyibe, Percin Ferda, Yuksel Nevzat, Guzey Cuneyt, Uluoglu Canan
Abstract excerpt
BACKGROUND: The ATP-binding cassette sub-family B member 1 (ABCB1) gene, which encodes the p-glycoprotein at the blood-brain barrier, is investigated for patients' susceptibility to major depressive disorder (MDD) and their therapeutic response to antidepressants. However, there is an inconsistency between the studies of different ethnic groups. The current study aimed to determine the potential correlations of...
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