Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Influence of C3435T Polymorphism of the ABCB1 Gene on Genetic Susceptibility to Depression and Treatment Response in Polish Population - Preliminary Report.

International journal of medical sciences - 1 Jan 2015

Jeleń Agnieszka Maria, Sałagacka Aleksandra, Żebrowska Marta Karolina, Mirowski Marek, Talarowska Monika, Gałecki Piotr, Balcerczak Ewa Izabela

Abstract excerpt

BACKGROUND: Despite the high prevalence of depression, the mechanism of the origin of this disease as well as the causes of resistance to therapy in some patients are still not fully understood. Increasingly, the possible role of genetic factors is considered. One of them is polymorphisms in the ABCB1 (MDR1) gene which encodes P-glycoprotein, responsible for the transport of xenobiotics, including antidepressant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder

Share to Poland

Share to Recurrence

Share to Severity of Illness Index

Share to Treatment Outcome

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26664259
DOI: 10.7150/ijms.13119
PMCID: PMC4661296

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Influence of C3435T Polymorphism of the ABCB1 Gene on Genetic Susceptibility to Depression and Treatment Response in Polish Population - Preliminary Report.PMID 26664259Read ↗

ABCB1 C3435T polymorphism is associated with susceptibility to major depression, but not with a clinical response to citalopram in a Turkish population.Semantic proximity Read ↗

ABCB1 C1236T, G2677TA and C3435T Genetic Polymorphisms and Antidepressant Response Phenotypes: Results from a Portuguese Major Depressive Disorder Cohort.Semantic proximity Read ↗

Antidepressants and ABCB1 gene C3435T functional polymorphism: a naturalistic study.Semantic proximity Read ↗

Common genetic polymorphisms in the ABCB1 gene are associated with risk of major depressive disorder in male Portuguese individuals.Semantic proximity Read ↗

Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population.Semantic proximity Read ↗

ABCB1 gene C3435T polymorphism and drug resistance in epilepsy: evidence based on 8,604 subjects.Semantic proximity Read ↗

Distribution of allelic variants of functional C3435T polymorphism of drug transporter MDR1 gene in a sample of Polish population.Semantic proximity Read ↗

[Characterisation of selected molecular mechanisms influencing pharmacokinetics and pharmacodynamics of antidepressants].Semantic proximity Read ↗

The ABCB1-C3435T polymorphism likely acts as a risk factor for resistance to antiepileptic drugs.Semantic proximity Read ↗

Importance of selected ABCB1 SNPs for the level of severity of depressive symptoms and effectiveness of recurrent depressive disorder therapy.Semantic proximity Read ↗

Association analysis of intractable epilepsy with C3435T and G2677T/A ABCB1 gene polymorphisms in Iranian patients.Semantic proximity Read ↗

ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.