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Article

ABCB1 genotyping in the treatment of depression.

Pharmacogenomics - 1 Dec 2016

Brückl Tanja Maria, Uhr Manfred

Abstract excerpt

P-glycoprotein (P-gp), the gene product of ABCB1, is a drug transporter at the blood-brain barrier and could be a limiting factor for entrance of antidepressants into the brain, the target site of antidepressant action. Animal studies showed that brain concentrations of many antidepressants depen...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Transport and Resistance Mechanisms

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 27918249
DOI: 10.2217/pgs.16.18

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-27918249-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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