Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MRP1 polymorphisms associated with citalopram response in patients with major depression.

Journal of clinical psychopharmacology - 1 Apr 2010

Lee Sung Hee, Lee Min-Soo, Lee Ji Hyun, Kim So Won, Kang Rhee-Hun, Choi Myoung-Jin, Park Sang Jin, Kim Se Joo, Lee Jae Myun, Cole Susan P C, Lee Min Goo

Abstract excerpt

Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic variations in MRP1/ABCC1 and the therapeutic response to the antidepressant citalopram. One hundred and twenty-three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Citalopram

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Follow-Up Studies

Share to Gene Frequency

Share to Multidrug Resistance-Associated Proteins

Share to Treatment Outcome

Share to Young Adult

Source

Identifiers

PMID: 20520284
DOI: 10.1097/JCP.0b013e3181d2ef42

Genes

ABCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MRP1 polymorphisms associated with citalopram response in patients with major depression.PMID 20520284Read ↗

ABCB1 gene polymorphisms are associated with the severity of major depressive disorder and its response to escitalopram treatment.Semantic proximity Read ↗

ABCB1 C3435T polymorphism is associated with susceptibility to major depression, but not with a clinical response to citalopram in a Turkish population.Semantic proximity Read ↗

MDR1 gene polymorphism: therapeutic response to paroxetine among patients with major depression.Semantic proximity Read ↗

ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder.Semantic proximity Read ↗

ABCB1 C1236T, G2677TA and C3435T Genetic Polymorphisms and Antidepressant Response Phenotypes: Results from a Portuguese Major Depressive Disorder Cohort.Semantic proximity Read ↗

ABCB6, ABCB1 and ABCG1 genetic polymorphisms and antidepressant response of SSRIs in Chinese depressive patients.Semantic proximity Read ↗

Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application.Semantic proximity Read ↗

ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression.Semantic proximity Read ↗

ABCB1 genotyping in the treatment of depression.Semantic proximity Read ↗

Association of ABCB1 gene variants, plasma antidepressant concentration, and treatment response: Results from a randomized clinical study.Semantic proximity Read ↗

Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population.Semantic proximity Read ↗

Effects of CYP2C19 genetic polymorphism on the steady-state concentration of citalopram in patients with major depressive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.