Article
MRP1 polymorphisms associated with citalopram response in patients with major depression.
Journal of clinical psychopharmacology - 1 Apr 2010
Lee Sung Hee, Lee Min-Soo, Lee Ji Hyun, Kim So Won, Kang Rhee-Hun, Choi Myoung-Jin, Park Sang Jin, Kim Se Joo, Lee Jae Myun, Cole Susan P C, Lee Min Goo
Abstract excerpt
Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic varia...
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