Article
Evaluation of the Role of ABCB1gene Polymorphic Variants on Psychiatric Disorders Predisposition in Macedonian Population.
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) - 1 Dec 2017
Naumovska Zorica, Nestorovska Aleksandra K, Sterjev Zoran, Filipce Ana, Grozdanova Aleksandra, Dimovski Aleksandar, Suturkova Ljubica, Serafimoski Vladimir
Abstract excerpt
The psychiatric and other CNS disorders are characterized with unregulated neuro-inflammatory processes and chronic microglia cell activation resulting with detrimental effect. ABCB1gene polymorphismsC1236T, G2677T/Aand C3435T are associated with P-glycoprotein expression and function andare linked with predisposition to psychiatric disorders such as schizophrenia and bipolar disorders. The relationship between...
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