Article
Significant survival impact of MACC1 polymorphisms in HER2 positive breast cancer patients.
European journal of cancer (Oxford, England : 1990) - 1 Aug 2014
Muendlein Axel, Hubalek Michael, Geller-Rhomberg Simone, Gasser Klaus, Winder Thomas, Drexel Heinz, Decker Thomas, Mueller-Holzner Elisabeth, Chamson Martina, Marth Christian, Lang Alois H
Abstract excerpt
BACKGROUND: Deregulation of hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (MET) signalling has been associated with poor clinical outcome in breast cancer and other cancers. The recently discovered metastasis-associated in colon cancer-1 (MACC1) gene is a key regulator o...
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