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Article

Unexpected domain composition of MACC1 links MET signaling and apoptosis.

4 Jun 2009

Abstract excerpt

Colorectal cancer, one of the most challenging malignancies, still has a limited number of recognized prognostic and predictive markers indicating appropriate treatment. MACC1 (metastasis-associated in colon cancer-1), a novel regulator of tumor growth and metastasis has recently been identified as an important prognostic factor of metastatic disease in colorectal cancer. The mechanism of MACC1 activity remains...

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PMID: 19499089
DOI: 10.18388/abp.2009_2464

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