Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A familial heterozygous null mutation of MET in autism spectrum disorder.

Autism research : official journal of the International Society for Autism Research - 1 Oct 2014

Lambert Nelle, Wermenbol Vanessa, Pichon Bruno, Acosta Sandra, van den Ameele Jelle, Perazzolo Camille, Messina Diana, Musumeci Maria-Franca, Dessars Barbara, De Leener Anne, Abramowicz Marc, Vilain Catheline

Abstract excerpt

Autism spectrum disorder (ASD) results from interactions of genetic and environmental factors. The MET proto-oncogene has been identified as a candidate gene for autism susceptibility, and is implicated in neurodevelopment and social brain circuitry. Here, we describe the first case of a familial mutation of MET, consisting of an interstitial genomic deletion removing exons 12 through 15, causing a frameshift and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child Development Disorders, Pervasive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Polymerase Chain Reaction

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins c-met

Share to Sequence Deletion

Source

Identifiers

PMID: 24909855
DOI: 10.1002/aur.1396

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A familial heterozygous null mutation of MET in autism spectrum disorder.PMID 24909855Read ↗

A genetic variant that disrupts MET transcription is associated with autism.Semantic proximity Read ↗

Disruption of cerebral cortex MET signaling in autism spectrum disorder.Semantic proximity Read ↗

Further evidence for the role of MET in autism susceptibility.Semantic proximity Read ↗

Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome.Semantic proximity Read ↗

Association of MET with social and communication phenotypes in individuals with autism spectrum disorder.Semantic proximity Read ↗

MET and autism susceptibility: family and case-control studies.Semantic proximity Read ↗

Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions.Semantic proximity Read ↗

Sequencing ASMT identifies rare mutations in Chinese Han patients with autism.Semantic proximity Read ↗

MET receptor tyrosine kinase as an autism genetic risk factor.Semantic proximity Read ↗

Replication of the association of a MET variant with autism in a Chinese Han population.Semantic proximity Read ↗

Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder.Semantic proximity Read ↗

Mutation screening of melatonin-related genes in patients with autism spectrum disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.