Article
Replication of the association of a MET variant with autism in a Chinese Han population.
PloS one - 1 Jan 2011
Zhou Xue, Xu Yang, Wang Jia, Zhou Hongbo, Liu Xian, Ayub Qasim, Wang Xuelai, Tyler-Smith Chris, Wu Lijie, Xue Yali
Abstract excerpt
BACKGROUND: Autism is a common, severe and highly heritable neurodevelopmental disorder in children, affecting up to 100 children per 10,000. The MET gene has been regarded as a promising candidate gene for this disorder because it is located within a replicated linkage interval, is involved in pathways affecting the development of the cerebral cortex and cerebellum in ways relevant to autism patients, and has...
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