Article
MET receptor tyrosine kinase as an autism genetic risk factor.
International review of neurobiology - 1 Jan 2013
Peng Yun, Huentelman Matthew, Smith Christopher, Qiu Shenfeng
Abstract excerpt
In this chapter, we will briefly discuss recent literature on the role of MET receptor tyrosine kinase (RTK) in brain development and how perturbation of MET signaling may alter normal neurodevelopmental outcomes. Recent human genetic studies have established MET as a risk factor for autism, and the molecular and cellular underpinnings of this genetic risk are only beginning to emerge from obscurity. Unlike many...
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