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Article

Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions.

Pediatrics - 1 Mar 2009

Campbell Daniel B, Buie Timothy M, Winter Harland, Bauman Margaret, Sutcliffe James S, Perrin James M, Levitt Pat

Abstract excerpt

OBJECTIVE: In addition to the core behavioral symptoms of autism spectrum disorder, many patients present with complex medical conditions including gastrointestinal dysfunction. A functional variant in the promoter of the gene encoding the MET receptor tyrosine kinase is associated with autism spectrum disorder, and MET protein expression is decreased in the temporal cortex of subjects with autism spectrum...

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Share to Receptors, Growth Factor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Share to Proto-Oncogene Proteins c-met

Source

Identifiers

PMID: 19255034
DOI: 10.1542/peds.2008-0819

Genes

MET

Provenance

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