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Article

A genetic variant that disrupts MET transcription is associated with autism.

Proceedings of the National Academy of Sciences of the United States of America - 7 Nov 2006

Campbell Daniel B, Sutcliffe James S, Ebert Philip J, Militerni Roberto, Bravaccio Carmela, Trillo Simona, Elia Maurizio, Schneider Cindy, Melmed Raun, Sacco Roberto, Persico Antonio M, Levitt Pat

Abstract excerpt

There is strong evidence for a genetic predisposition to autism and an intense interest in discovering heritable risk factors that disrupt gene function. Based on neurobiological findings and location within a chromosome 7q31 autism candidate gene region, we analyzed the gene encoding the pleiotropic MET receptor tyrosine kinase in a family based study of autism including 1,231 cases. MET signaling participates...

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Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins c-met

Share to Receptors, Growth Factor

Share to Transcription, Genetic

Source

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Identifiers

PMID: 17053076
DOI: 10.1073/pnas.0605296103
PMCID: PMC1838551

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A genetic variant that disrupts MET transcription is associated with autism.PMID 17053076Read ↗

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Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder.Semantic proximity Read ↗

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