Article
MET and autism susceptibility: family and case-control studies.
European journal of human genetics : EJHG - 1 Jun 2009
Sousa Inês, Clark Taane G, Toma Claudio, Kobayashi Kazuhiro, Choma Maja, Holt Richard, Sykes Nuala H, Lamb Janine A, Bailey Anthony J, Battaglia Agatino, Maestrini Elena, Monaco Anthony P
Abstract excerpt
Autism is a common, severe and highly heritable neurodevelopmental disorder. The International Molecular Genetic Study of Autism Consortium (IMGSAC) genome screen for linkage in affected sib-pair families identified a chromosome 7q susceptibility locus (AUTS1), that has subsequently shown evidence of increased sharing in several independent multiplex samples and in two meta-analyses. Taking into account the...
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