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Article

Role of Leukocyte Cell-Derived Chemotaxin 2 as a Biomarker in Hepatocellular Carcinoma

3 Jun 2014

Abstract excerpt

We sought to identify a secreted biomarker for β-catenin activation commonly seen in hepatocellular carcinoma (HCC). By examination of our previously published genearray of hepatocyte-specific β-catenin knockout (KO) livers, we identified secreted factors whose expression may be β-catenin-dependent. We verified expression and secretion of the leading factor in HCC cells transfected with mutated...

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Share to Hepatocellular Carcinoma Treatment and Prognosis
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Share to Wnt/β-catenin signaling in development and cancer

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PMID: 24892551
DOI: 10.1371/journal.pone.0098817

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