Article
Postsynaptic potentiation of corticospinal projecting neurons in the anterior cingulate cortex after nerve injury.
Molecular pain - 3 Jun 2014
Chen Tao, Koga Kohei, Descalzi Giannina, Qiu Shuang, Wang Jian, Zhang Le-Shi, Zhang Zhi-Jian, He Xiao-Bin, Qin Xin, Xu Fu-Qiang, Hu Ji, Wei Feng, Huganir Richard L, Li Yun-Qing, Zhuo Min
Abstract excerpt
Long-term potentiation (LTP) is the key cellular mechanism for physiological learning and pathological chronic pain. In the anterior cingulate cortex (ACC), postsynaptic recruitment or modification of AMPA receptor (AMPAR) GluA1 contribute to the expression of LTP. Here we report that pyramidal cells in the deep layers of the ACC send direct descending projecting terminals to the dorsal horn of the spinal cord...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
