Article
GluA1 phosphorylation contributes to postsynaptic amplification of neuropathic pain in the insular cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 2014
Qiu Shuang, Zhang Ming, Liu Yan, Guo Yanyan, Zhao Huan, Song Qian, Zhao Minggao, Huganir Richard L, Luo Jianhong, Xu Hui, Zhuo Min
Abstract excerpt
Long-term potentiation of glutamatergic transmission has been observed after physiological learning or pathological injuries in different brain regions, including the spinal cord, hippocampus, amygdala, and cortices. The insular cortex is a key cortical region that plays important roles in aversive learning and neuropathic pain. However, little is known about whether excitatory transmission in the insular cortex...
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