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Article

Functional annotation signatures of disease susceptibility loci improve SNP association analysis.

BMC genomics - 24 May 2014

Iversen Edwin S, Lipton Gary, Clyde Merlise A, Monteiro Alvaro N A

Abstract excerpt

BACKGROUND: Genetic association studies are conducted to discover genetic loci that contribute to an inherited trait, identify the variants behind these associations and ascertain their functional role in determining the phenotype. To date, functional annotations of the genetic variants have rarely played more than an indirect role in assessing evidence for association. Here, we demonstrate how these data can be...

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Identifiers

PMID: 24886216
DOI: 10.1186/1471-2164-15-398
PMCID: PMC4041996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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