Article

Functional Annotation Signatures of Disease Susceptibility Loci Improve SNP Association Analysis

2013-11-11

Abstract excerpt

We describe the development and application of a Bayesian statistical model for the prior probability of phenotype–genotype association that incorporates data from past association studies and publicly available functional annotation data regarding the susceptibility variants under study. The model takes the form of a binary regression of association status on a set of annotation variables whose coefficients were...

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Literature Corpus work: 74eac89a-ef22-541b-9423-7df946bb4ef5
DOI: 10.1101/000158

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