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Article

Leveraging functional annotations in genetic risk prediction for human complex diseases.

PLoS computational biology - 1 Jun 2017

Hu Yiming, Lu Qiongshi, Powles Ryan, Yao Xinwei, Yang Can, Fang Fang, Xu Xinran, Zhao Hongyu

Abstract excerpt

Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite the identification of thousands of disease-associated genetic variants through genome wide association studies (GWAS), genetic risk prediction accuracy remains moderate for most diseases, which is...

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Identifiers

PMID: 28594818
DOI: 10.1371/journal.pcbi.1005589
PMCID: PMC5481142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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