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Article

Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors.

BMC genetics - 30 May 2014

Zhu Rui, Matin Angabin

Abstract excerpt

BACKGROUND: Complex genetic factors underlie testicular germ cell tumor (TGCT) development. One experimental approach to dissect the genetics of TGCT predisposition is to use chromosome substitution strains, such as the 129.MOLF-Chr 19 (M19). M19 carries chromosome (Chr) 19 from the MOLF whereas all other chromosomes are from the 129 strain. 71% of M19 males develop TGCTs in contrast to 5% in 129 strain. To...

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Identifiers

PMID: 24886204
DOI: 10.1186/1471-2156-15-65
PMCID: PMC4053281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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