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Article

Genetic control of susceptibility to spontaneous testicular germ cell tumors in mice.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2003

Lam Man-Yee Josephine, Nadeau Joseph H

Abstract excerpt

Testicular germ cell tumors (TGCTs) are the most common cancer affecting young men. TGCT is a polygenic trait and genes that control susceptibility for TGCT development have not yet been identified. The 129/Sv inbred strain of mice is an important experimental model to study the genetics and development of TGCTs. We review several novel approaches that were developed to study the susceptibility of TGCTs in the...

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Identifiers

PMID: 12752260
DOI: 10.1034/j.1600-0463.2003.11101221.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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