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Article

Testicular germ cell tumors in mice: new ways to study a genetically complex trait.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Heaney Jason D, Nadeau Joseph H

Abstract excerpt

Testicular germ cell tumors (TGCTs) are the most common cancer affecting young men. Although TGCTs are common and the genetic component of susceptibility is unusually strong, discovery of TGCT susceptibility genes in humans has been challenging. The 129/Sv inbred mouse strain is an important experimental model for studying the genetic control of TGCT susceptibility. It is the only inbred mouse strain with an...

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Source

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PMID: 18370062
DOI: 10.1007/978-1-60327-214-8_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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