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Phenotype and gene signature of testicular tumors in 129.MOLF-Chr19 mice resemble human teratomas.

Andrology - 1 Jul 2025

Gayer Fabian A, Klaus Lucas, Reichardt Sybille D, Fichtner Alexander, Reichardt Holger M

Abstract excerpt

BACKGROUND: Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal-type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal-type teratomas arise independently of the GCNIS. The consomic mouse strain 129.MOLF-Chr19 (M19) is a suitable murine model of such tumors, but its characterization remains...

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Disease Models, Animal
Mice
Neoplasms, Germ Cell and Embryonal
Phenotype
Teratoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Testicular Neoplasms

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PMID: 39074032
DOI: 10.1111/andr.13717
PMCID: PMC12183013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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