Article
Enhancers and suppressors of testicular cancer susceptibility in single- and double-mutant mice.
Genetics - 1 Feb 2004
Lam Man-Yee Josephine, Youngren Kirsten K, Nadeau Joseph H
Abstract excerpt
Susceptibility to spontaneous testicular germ cell tumors (TGCTs), a common cancer affecting young men, shows unusual genetic complexity. Despite remarkable progress in the genetics analysis of susceptibility to many cancers, TGCT susceptibility genes have not yet been identified. Various mutations that are inherited as Mendelian traits in laboratory mice affect susceptibility to spontaneous TGCTs on the 129/Sv...
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