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Article

From genes to function: the C. elegans genetic toolbox.

Wiley interdisciplinary reviews. Developmental biology - 1 Jan 2000

Boulin Thomas, Hobert Oliver

Abstract excerpt

This review aims to provide an overview of the technologies which make the nematode Caenorhabditis elegans an attractive genetic model system. We describe transgenesis techniques and forward and reverse genetic approaches to isolate mutants and clone genes. In addition, we discuss the new possibilities offered by genome engineering strategies and next-generation genome analysis tools.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23801671
DOI: 10.1002/wdev.1
PMCID: PMC3694748

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