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Article

Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance.

Cell cycle (Georgetown, Tex.) - 1 Jan 2014

Rachdi Latif, Kariyawasam Dulanjalee, Aïello Virginie, Herault Yann, Janel Nathalie, Delabar Jean-Maurice, Polak Michel, Scharfmann Raphaël

Abstract excerpt

Type 2 diabetes is caused by a limited capacity of insulin-producing pancreatic β cells to increase their mass and function in response to insulin resistance. The signaling pathways that positively regulate functional β cell mass have not been fully elucidated. DYRK1A (also called minibrain/MNB) is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. A significant amount of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24870561
DOI: 10.4161/cc.29250
PMCID: PMC4111677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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