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Article

KRAS oncogene substitutions in Korean NSCLC patients: clinical implication and relationship with pAKT and RalGTPases expression.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2014

Kim Eun Young, Kim Arum, Kim Se Kyu, Kim Hyung Jung, Chang Joon, Ahn Chul Min, Lee Jae Seok, Shim Hyo Sup, Chang Yoon Soo

Abstract excerpt

OBJECTIVES: Since different conformation of each KRAS mutant leads to inherent downstream signaling, its distribution, influence on the clinical outcome, and effect on the signaling mediators were investigated in the Korean NSCLC patients whose tumor have KRAS mutation. MATERIALS AND METHODS: Mutation at KRAS codons 12 and 13 was evaluated in 1420 Korean NSCLC by direct sequencing and expression of RalA, RalB,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24863005
DOI: 10.1016/j.lungcan.2014.04.012

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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