Article
Clinical characteristics of KRAS mutation subtypes in non-small cell lung cancer population in Xinjiang, China, and their impact on the prognosis of immunotherapy.
Journal of cancer research and clinical oncology - 7 Sept 2024
Gu Guomin, Liu Chunling, Zhu Xiaodan, Yang Yan, Song Shuming, Zhao Yan, Sun Gang
Abstract excerpt
PURPOSE: Non-small cell lung cancer (NSCLC) is a highly fatal malignancy. The Kirsten rat sarcoma viral oncogene (KRAS) gene profoundly impacts patient prognosis. This study aims to explore the correlation between KRAS mutation subtypes, clinical data, and the impact of these subtypes on immunotherapy. MATERIALS AND METHODS: Tumor samples from 269 NSCLC patients at the Affiliated Cancer Hospital of Xinjiang...
Topics
- Humans
- Carcinoma, Non-Small-Cell Lung
- Male
- Proto-Oncogene Proteins p21(ras)
- Female
- Lung Neoplasms
- Middle Aged
- Mutation
- Prognosis
- China
- Aged
- Immunotherapy
- Adult
- Aged, 80 and over