The prevalence and prognostic significance of KRAS mutation subtypes in lung adenocarcinomas from Chinese populations

Abstract excerpt

BACKGROUND: We performed this retrospective study to identify the prevalence of KRAS mutation in Chinese populations and make a comprehensive investigation of the clinicopathological features of KRAS mutation in these patients. PATIENTS AND METHODS: Patients from 2007 to 2013 diagnosed with primary lung adeno-carcinoma who received a radical resection were examined for KRAS, EGFR, HER2, BRAF mutations, and ALK,...

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