Article
The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma.
Yonsei medical journal - 1 Jul 2013
Kim Hye Ryun, Ahn Jung Ryun, Lee Jin Gu, Bang Doo Hee, Ha Sang-Jun, Hong Yun Kyoung, Kim Sun Mi, Nam Ki Chang, Rha Sun Young, Soo Ross A, Riely Gregory J, Kim Joo Hang, Cho Byoung Chul
Abstract excerpt
PURPOSE: This study was designed to determine the relationship of cigarette smoking to the frequency and qualitative differences among KRAS mutations in lung adenocarcinomas from Korean patients. MATERIALS AND METHODS: Detailed smoking histories were obtained from 200 consecutively enrolled patients with lung adenocarcinoma according to a standard protocol. EGFR (exons 18 to 21) and KRAS (codons 12/13) mutations...
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