Article

Differential properties of KRAS transversion and transition mutations in non-small lung cancer: associations with environmental factors and clinical outcomes

2022-05-09

Abstract excerpt

<h4>Background: </h4> KRAS -mutated non-small cell lung cancer (NSCLC) accounts for 23–35% and 13–20% of all NSCLCs in Caucasians and East Asians, respectively, and is therefore regarded as a major therapeutic target. However, its epidemiology and clinical characteristics have not been fully elucidated because of its wide variety of mutational subtypes. Here, we focused on two distinct base substitution types: tra...

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Literature Corpus work: 6d34b6c8-5a68-596a-bac7-8d75a8e683cf
DOI: 10.21203/rs.3.rs-1584892/v1

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