Article
KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer: a cohort study.
BMJ open - 23 May 2014
Negru Serban, Papadopoulou Eirini, Apessos Angela, Stanculeanu Dana Lucia, Ciuleanu Eliade, Volovat Constantin, Croitoru Adina, Kakolyris Stylianos, Aravantinos Gerasimos, Ziras Nikolaos, Athanasiadis Elias, Touroutoglou Nikolaos, Pavlidis Nikolaos, Kalofonos Haralabos P, Nasioulas George
Abstract excerpt
OBJECTIVES: Treatment decision-making in colorectal cancer is often guided by tumour tissue molecular analysis. The aim of this study was the development and validation of a high-resolution melting (HRM) method for the detection of KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer and determination of the frequency of these mutations in the respective populations. SETTING:...
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