Article
Genetics of ANCA-associated vasculitides: HLA and beyond.
Clinical and experimental rheumatology - 1 Jan 2000
Alberici Federico, Martorana Davide, Bonatti Francesco, Gioffredi Andrea, Lyons Paul A, Vaglio Augusto
Abstract excerpt
The pathogenesis of ANCA-associated vasculitis (AAV) is multifactorial and most likely involves the interaction of environmental and genetic factors. During the past few years, a number of studies have investigated genetic associations with AAV; earlier studies explored associations with single nucleotide polymorphisms (SNPs) at genes of potential pathogenetic interest ('candidate gene' studies), whereas more...
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