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Genetic aspects of anti-neutrophil cytoplasmic antibody-associated vasculitis

18 Dec 2014

Abstract excerpt

The genetics of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a complex area of investigation because of the low frequency of AAVs, the rarity of familial cases and the complexity of disease phenotypes. However, recent studies have been able to gather significant numbers of patients, and multicentre collaborative efforts have allowed the performance of two genome-wide association...

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PMID: 25523449
DOI: 10.1093/ndt/gfu386

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