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Article

The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population.

RMD open - 4 Apr 2024

Lundtoft Christian, Knight Ann, Meadows Jennifer R S, Karlsson Åsa, Rantapää-Dahlqvist Solbritt, Berglin Ewa, Palm Øyvind, Haukeland Hilde, Gunnarsson Iva, Bruchfeld Annette, Segelmark Mårten, Ohlsson Sophie, Mohammad Aladdin J, Eriksson Per, Söderkvist Peter, Ronnblom Lars, Omdal Roald, Jonsson Roland, Lindblad-Toh Kerstin, Dahlqvist Johanna

Abstract excerpt

OBJECTIVE: The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are inflammatory disorders with ANCA autoantibodies recognising either proteinase 3 (PR3-AAV) or myeloperoxidase (MPO-AAV). PR3-AAV and MPO-AAV have been associated with distinct loci in the human leucocyte antigen (HLA) region. While the association between MPO-AAV and HLA has been well characterised in East Asian populations...

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Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Antibodies, Antineutrophil Cytoplasmic
Genotype
Recurrence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38580345
DOI: 10.1136/rmdopen-2023-004039
PMCID: PMC11002376

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