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Article

Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.

Human molecular genetics - 15 Oct 2014

Zhan Ming, Chen Gang, Pan Chun-Ming, Gu Zhao-Hui, Zhao Shuang-Xia, Liu Wei, Wang Hai-Ning, Ye Xiao-Ping, Xie Hui-Jun, Yu Sha-Sha, Liang Jun, Gao Guan-Qi, Yuan Guo-Yue, Zhang Xiao-Mei, Zuo Chun-Lin, Su Bin, Huang Wei, Ning Guang, Chen Sai-Juan, Chen Jia-Lun, Song Huai-Dong

Abstract excerpt

Thyroid-stimulating hormone (TSH) is a sensitive indicator of thyroid function. High and low TSH levels reflect hypothyroidism and hyperthyroidism, respectively. Even within the normal range, small differences in TSH levels, on the order of 0.5-1.0 mU/l, are associated with significant differences in blood pressure, BMI, dyslipidemia, risk of atrial fibrillation and atherosclerosis. Most of the variance in TSH...

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Source

Identifiers

PMID: 24852370
DOI: 10.1093/hmg/ddu250

Genes

FOXE1
XKR4
CAPZB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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