Article
Cellular senescence and the senescent secretory phenotype in age-related chronic diseases.
Current opinion in clinical nutrition and metabolic care - 1 Jul 2014
Zhu Yi, Armstrong Jacqueline L, Tchkonia Tamara, Kirkland James L
Abstract excerpt
PURPOSE OF REVIEW: Possible mechanisms in cellular senescence and the senescence-associated secretory phenotype (SASP) that drive and promote chronic inflammation in multiple age-related chronic diseases are considered. RECENT FINDINGS: A series of studies about the SASP indicate that senescent cells may be involved in the development of chronic inflammatory diseases associated with aging. SUMMARY: Aging is a...
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