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Article

The multifaceted role of the SASP in atherosclerosis: from mechanisms to therapeutic opportunities

31 May 2022

Abstract excerpt

BACKGROUND: The global population of older individuals is growing, and ageing is a key risk factor for atherosclerotic cardiovascular diseases. Abnormal accumulation of senescent cells can cause potentially deleterious effects on the organism with age. As a vital marker of cellular senescence, the senescence-associated secretory phenotype (SASP) is a novel mechanism to link cellular senescence with...

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Share to Epigenetics and DNA Methylation
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Telomeres, Telomerase, and Senescence

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PMID: 35642067
DOI: 10.1186/s13578-022-00815-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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