Article
Multiple genome modifications by the CRISPR/Cas9 system in zebrafish.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2014
Ota Satoshi, Hisano Yu, Ikawa Yoshiya, Kawahara Atsuo
Abstract excerpt
The type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system, which is an adaptive immune system of bacteria, has become a powerful tool for genome editing in various model organisms. Here, we demonstrate multiple genome modifications mediated by CRISPR/Cas9 in zebrafish (Danio rerio). Multiple genes including golden/gol and tyrosinase/tyr, which are involved in...
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