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Article

Detection of Multiple Genome Modifications Induced by the CRISPR/Cas9 System.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Ota Satoshi, Kawahara Atsuo

Abstract excerpt

The recent remarkable innovation of an RNA-guided nuclease system, the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system, enables us the modification of specific genomic loci in various model animals including zebrafish. With this system, multiple guide RNAs simultaneously injected with the Cas9 nuclease into zebrafish embryos cause multiple genome modifications at...

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PMID: 27464800
DOI: 10.1007/978-1-4939-3771-4_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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