Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos.

Cell research - 1 Apr 2013

Chang Nannan, Sun Changhong, Gao Lu, Zhu Dan, Xu Xiufei, Zhu Xiaojun, Xiong Jing-Wei, Xi Jianzhong Jeff

Abstract excerpt

Recent advances with the type II clustered regularly interspaced short palindromic repeats (CRISPR) system promise an improved approach to genome editing. However, the applicability and efficiency of this system in model organisms, such as zebrafish, are little studied. Here, we report that RNA-guided Cas9 nuclease efficiently facilitates genome editing in both mammalian cells and zebrafish embryos in a simple...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryo, Nonmammalian
Share to Fish Proteins
Share to GATA Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Reverse Genetics

Share to Ribonucleases

Share to RNA Editing

Share to RNA, Small Untranslated

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23528705
DOI: 10.1038/cr.2013.45
PMCID: PMC3616424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos.PMID 23528705Read ↗

Targeted Mutagenesis in Zebrafish Using CRISPR RNA-Guided Nucleases.Semantic proximity Read ↗

Efficient genome editing in zebrafish using a CRISPR-Cas system.Semantic proximity Read ↗

Generation of Targeted Mutations in Zebrafish Using the CRISPR/Cas System.Semantic proximity Read ↗

Generation of zebrafish models by CRISPR /Cas9 genome editing.Semantic proximity Read ↗

Recent advances in CRISPR-based genome editing technology and its applications in cardiovascular researchSemantic proximity Read ↗

CRISPR/Cas9 in zebrafish: an efficient combination for human genetic diseases modelingSemantic proximity Read ↗

A CRISPR view of development.Semantic proximity Read ↗

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.Semantic proximity Read ↗

Programmable RNA targeting with clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas7-11 in zebrafish embryos and mammalian cellsSemantic proximity Read ↗

Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease.Semantic proximity Read ↗

Enhance genome editing efficiency and specificity by a quick CRISPR/Cas9 systemSemantic proximity Read ↗

Detection of Multiple Genome Modifications Induced by the CRISPR/Cas9 System.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.