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Article

Positive and negative gustatory inputs affect Drosophila lifespan partly in parallel to dFOXO signaling.

Proceedings of the National Academy of Sciences of the United States of America - 3 Jun 2014

Ostojic Ivan, Boll Werner, Waterson Michael J, Chan Tammy, Chandra Rashmi, Pletcher Scott D, Alcedo Joy

Abstract excerpt

In Caenorhabditis elegans, a subset of gustatory neurons, as well as olfactory neurons, shortens lifespan, whereas a different subset of gustatory neurons lengthens it. Recently, the lifespan-shortening effect of olfactory neurons has been reported to be conserved in Drosophila. Here we show that the Drosophila gustatory system also affects lifespan in a bidirectional manner. We find that taste inputs shorten...

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Identifiers

PMID: 24847072
DOI: 10.1073/pnas.1315466111
PMCID: PMC4050613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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