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Article

Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans.

PLoS genetics - 1 Jan 2012

Gaglia Marta M, Jeong Dae-Eun, Ryu Eun-A, Lee Dongyeop, Kenyon Cynthia, Lee Seung-Jae

Abstract excerpt

The sensory systems of multicellular organisms are designed to provide information about the environment and thus elicit appropriate changes in physiology and behavior. In the nematode Caenorhabditis elegans, sensory neurons affect the decision to arrest during development in a diapause state, the dauer larva, and modulate the lifespan of the animals in adulthood. However, the mechanisms underlying these effects...

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PMID: 23284299
DOI: 10.1371/journal.pgen.1003133
PMCID: PMC3527274

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