Article

Gut-to-brain regulation of <i>Drosophila</i> aging through neuropeptide F, insulin and juvenile hormone

2024-06-30

Abstract excerpt

Dietary restriction slows aging in many animals, while in some cases the sensory signals from diet alone are sufficient to retard or accelerate lifespan. The digestive tract is a candidate location to sense nutrients, where neuropeptides secreted by enteroendocrine cells (EEC) produce systemic signals in response to food. Here we measure how Drosophila neuropeptide F (NPF) is secreted into adult circulation by en...

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Literature Corpus work: f6094e71-0973-5dc0-b6b6-1cdb2275ed63
DOI: 10.1101/2024.06.26.600832

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