The role of the RTEL1 rs2297440 polymorphism in the risk of glioma development: a meta-analysis.

doi:10.1007/s10072-016-2531-z

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Article

The role of the RTEL1 rs2297440 polymorphism in the risk of glioma development: a meta-analysis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Jul 2016

Zhang Cuiping, Lu Yu, Zhang Xiaolian, Yang Dongmei, Shang Shuxin, Liu Denghe, Jiang Kongmei, Huang Weiqiang

Abstract excerpt

The regulator of the telomere elongation helicase1 (RTEL1) gene plays a crucial role in the DNA double-stand break-repair pathway by maintaining genomic stability. Recent epidemiological studies showed that the rs2297440 polymorphism in the RTEL1 gene was a potential risk locus for glioma development, but the results were inconclusive. To clarify the association between this polymorphism and the risk of glioma,...

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PMID: 26939676
DOI: 10.1007/s10072-016-2531-z

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RTEL1

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