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Article

The role of PTEN tumor suppressor pathway staining in carcinoma in situ of the bladder.

Urologic oncology - 1 Jul 2014

Sfakianos John P, Lin Gellert Lan, Maschino Alexandra, Gotto Geoffrey T, Kim Philip H, Al-Ahmadie Hikmat, Bochner Bernard H

Abstract excerpt

OBJECTIVES: The PI3k/Akt pathway has been associated with the development and progression of bladder tumors, with most studies focused on papillary or muscle-invasive tumors. We sought to characterize the expression patterns of the PI3K/Akt pathway in a large cohort of high-risk preinvasive carcinoma in situ (CIS) tumors of the bladder. Our goal was to understand whether PI3K/Akt pathway alterations associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-akt

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Source

Open in PubMed Open full text

Identifiers

PMID: 24840867
DOI: 10.1016/j.urolonc.2014.02.003
PMCID: PMC4062573

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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