Article
Evolution of HIV-1 quasispecies and coreceptor use in cell reservoirs of patients on suppressive antiretroviral therapy.
The Journal of antimicrobial chemotherapy - 1 Sept 2014
Raymond Stéphanie, Saliou Adrien, Delobel Pierre, Cazabat Michelle, Pasquier Christophe, Jeanne Nicolas, Sauné Karine, Massip Patrice, Marchou Bruno, Izopet Jacques
Abstract excerpt
OBJECTIVES: To track changes in the V3 env region of HIV-1 quasispecies and determine virus coreceptor use in cell reservoirs of patients on long-term suppressive antiretroviral therapy (ART). PATIENTS AND METHODS: Ten patients whose plasma viraemia had been suppressed for a median of 5.5 years were followed for 5 years. The V3 env regions of viruses in peripheral blood mononuclear cells were analysed by...
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